W11L (p.Trp11Leu) variant of PCSK9 (Proprotein convertase subtilisin/kexin type 9)
W11L (p.Trp11Leu) in PCSK9 (Proprotein convertase subtilisin/kexin type 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
W11L (p.Trp11Leu) variant details
- p.Trp11Leu
- gnomAD 1-55039869-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.16
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.20
- MetaSVM -0.88
- CADD 16.00
- Population evidence available
- Structural context available
- Literature evidence available