W10S (p.Trp10Ser) variant of PCSK9 (Proprotein convertase subtilisin/kexin type 9)
W10S (p.Trp10Ser) in PCSK9 (Proprotein convertase subtilisin/kexin type 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
W10S (p.Trp10Ser) variant details
- p.Trp10Ser
- gnomAD 1-55039866-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.13
- MetaSVM -1.02
- CADD 16.30
- Population evidence available
- Structural context available
- Literature evidence available