G36V (p.Gly36Val) variant of PCSK9 (Proprotein convertase subtilisin/kexin type 9)
G36V (p.Gly36Val) in PCSK9 (Proprotein convertase subtilisin/kexin type 9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes structural context.
G36V (p.Gly36Val) variant details
- p.Gly36Val
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.11
- MetaLR 0.15
- MetaSVM -0.96
- SIFT 0.06
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available