D35D (p.Asp35Asp) variant of PCSK9 (Proprotein convertase subtilisin/kexin type 9)
D35D (p.Asp35Asp) in PCSK9 (Proprotein convertase subtilisin/kexin type 9) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
D35D (p.Asp35Asp) variant details
- p.Asp35Asp
- rs533474523
- gnomAD 1-55039942-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.136
- CADD 7.82
- Most common in the HGDP:BRAHUI population (allele frequency 0.065)
- Structural context available
- Literature evidence available