D33D (p.Asp33Asp) variant of PCSK9 (Proprotein convertase subtilisin/kexin type 9)
D33D (p.Asp33Asp) in PCSK9 (Proprotein convertase subtilisin/kexin type 9) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
D33D (p.Asp33Asp) variant details
- p.Asp33Asp
- gnomAD 1-55039936-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.256
- CADD 7.63
- Most common in the HGDP:BERGAMOITALIAN population (allele frequency 0.045)
- Structural context available
- Literature evidence available