p.Arg72dup variant of PARP2 (Poly [ADP-ribose] polymerase 2)
p.Arg72dup in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
p.Arg72dup variant details
- gnomAD 14-20345096-G-GGA
- Inframe Insertion
- Variant Prioritization Score for Impact Estimate 0.119
- CADD 2.57
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available