S8R (p.Ser8Arg) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
S8R (p.Ser8Arg) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
S8R (p.Ser8Arg) variant details
- p.Ser8Arg
- gnomAD 14-20343665-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0582
- REVEL 0.03
- CADD 3.58
- PolyPhen-2 0.00
- SIFT 0.51
- Population evidence available
- Structural context available
- Literature evidence available