S8G (p.Ser8Gly) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
S8G (p.Ser8Gly) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
S8G (p.Ser8Gly) variant details
- p.Ser8Gly
- gnomAD 14-20343663-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.01
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.97
- Population evidence available
- Structural context available
- Literature evidence available