S47W (p.Ser47Trp) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
S47W (p.Ser47Trp) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
S47W (p.Ser47Trp) variant details
- p.Ser47Trp
- gnomAD 14-20345025-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.08
- CADD 10.60
- PolyPhen-2 0.06
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available