S34Y (p.Ser34Tyr) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
S34Y (p.Ser34Tyr) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
S34Y (p.Ser34Tyr) variant details
- p.Ser34Tyr
- gnomAD 14-20344986-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.09
- CADD 16.30
- PolyPhen-2 0.16
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available