S20I (p.Ser20Ile) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
S20I (p.Ser20Ile) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
S20I (p.Ser20Ile) variant details
- p.Ser20Ile
- gnomAD 14-20344944-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- REVEL 0.03
- CADD 9.54
- PolyPhen-2 0.01
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available