R44G (p.Arg44Gly) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
R44G (p.Arg44Gly) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
R44G (p.Arg44Gly) variant details
- p.Arg44Gly
- rs1433531281
- gnomAD 14-20345015-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.11
- CADD 22.50
- PolyPhen-2 0.03
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available