R41T (p.Arg41Thr) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
R41T (p.Arg41Thr) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
R41T (p.Arg41Thr) variant details
- p.Arg41Thr
- gnomAD 14-20345007-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0781
- REVEL 0.02
- CADD 10.10
- PolyPhen-2 0.00
- SIFT 0.42
- Population evidence available
- Structural context available
- Literature evidence available