R41K (p.Arg41Lys) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
R41K (p.Arg41Lys) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
R41K (p.Arg41Lys) variant details
- p.Arg41Lys
- gnomAD 14-20345007-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0894
- REVEL 0.04
- CADD 9.02
- PolyPhen-2 0.00
- SIFT 0.50
- Population evidence available
- Structural context available
- Literature evidence available