R22T (p.Arg22Thr) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
R22T (p.Arg22Thr) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
R22T (p.Arg22Thr) variant details
- p.Arg22Thr
- rs370855552
- gnomAD 14-20344950-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.03
- CADD 6.11
- PolyPhen-2 0.04
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available