R15K (p.Arg15Lys) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
R15K (p.Arg15Lys) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
R15K (p.Arg15Lys) variant details
- p.Arg15Lys
- rs1444241687
- gnomAD 14-20343685-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0868
- REVEL 0.03
- CADD 13.20
- PolyPhen-2 0.01
- SIFT 0.41
- Population evidence available
- Structural context available
- Literature evidence available