R15G (p.Arg15Gly) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
R15G (p.Arg15Gly) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
R15G (p.Arg15Gly) variant details
- p.Arg15Gly
- rs200603922
- gnomAD 14-20343684-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.01
- CADD 16.50
- PolyPhen-2 0.00
- SIFT 0.15
- Population evidence available
- Structural context available
- Cited in: Germline Sequencing of DNA Damage Repair Genes in Two Hereditary Prostate Cancer Cohorts Reveals New Disease… (PMID 39001544)