P51T (p.Pro51Thr) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
P51T (p.Pro51Thr) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
P51T (p.Pro51Thr) variant details
- p.Pro51Thr
- gnomAD 14-20345036-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.06
- CADD 10.20
- PolyPhen-2 0.10
- SIFT 0.04
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available
- Literature evidence available