N27T (p.Asn27Thr) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
N27T (p.Asn27Thr) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
N27T (p.Asn27Thr) variant details
- p.Asn27Thr
- gnomAD 14-20344965-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0969
- REVEL 0.04
- AlphaMissense 0.62
- MetaLR 0.00
- MetaSVM -0.84
- CADD 4.49
- PolyPhen-2 1.00
- Population evidence available
- Structural context available
- Literature evidence available