K59N (p.Lys59Asn) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
K59N (p.Lys59Asn) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
K59N (p.Lys59Asn) variant details
- p.Lys59Asn
- gnomAD 14-20345062-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0932
- REVEL 0.01
- CADD 7.23
- PolyPhen-2 0.00
- SIFT 0.29
- Population evidence available
- Structural context available
- Literature evidence available