K59E (p.Lys59Glu) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
K59E (p.Lys59Glu) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
K59E (p.Lys59Glu) variant details
- p.Lys59Glu
- rs762055576
- gnomAD 14-20345060-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0731
- REVEL 0.00
- AlphaMissense 0.07
- MetaLR 0.04
- MetaSVM -1.05
- CADD 0.68
- PolyPhen-2 0.00
- Population evidence available
- Structural context available
- Literature evidence available