K38R (p.Lys38Arg) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
K38R (p.Lys38Arg) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
K38R (p.Lys38Arg) variant details
- p.Lys38Arg
- gnomAD 14-20344998-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.05
- AlphaMissense 0.21
- MetaLR 0.00
- MetaSVM -0.81
- CADD 16.60
- PolyPhen-2 0.14
- Population evidence available
- Structural context available
- Literature evidence available