K21Q (p.Lys21Gln) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
K21Q (p.Lys21Gln) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
K21Q (p.Lys21Gln) variant details
- p.Lys21Gln
- rs1299062113
- gnomAD 14-20344946-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0803
- REVEL 0.01
- CADD 2.32
- PolyPhen-2 0.00
- SIFT 0.41
- Population evidence available
- Structural context available
- Literature evidence available