G71S (p.Gly71Ser) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
G71S (p.Gly71Ser) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
G71S (p.Gly71Ser) variant details
- p.Gly71Ser
- rs200569736
- gnomAD 14-20345420-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.32
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available