G54R (p.Gly54Arg) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
G54R (p.Gly54Arg) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
G54R (p.Gly54Arg) variant details
- p.Gly54Arg
- gnomAD 14-20345045-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.03
- AlphaMissense 0.14
- MetaLR 0.09
- MetaSVM -1.00
- CADD 10.90
- PolyPhen-2 0.21
- Population evidence available
- Structural context available
- Literature evidence available