G26D (p.Gly26Asp) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
G26D (p.Gly26Asp) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
G26D (p.Gly26Asp) variant details
- p.Gly26Asp
- rs1381122398
- gnomAD 14-20344962-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.06
- AlphaMissense 0.69
- MetaLR 0.54
- MetaSVM 0.26
- CADD 15.20
- PolyPhen-2 1.00
- Population evidence available
- Structural context available
- Literature evidence available