G12S (p.Gly12Ser) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
G12S (p.Gly12Ser) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data, published literature, and structural context.
G12S (p.Gly12Ser) variant details
- p.Gly12Ser
- rs779597599
- gnomAD 14-20343675-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0408
- REVEL 0.03
- CADD 0.13
- PolyPhen-2 0.00
- SIFT 0.46
- Population evidence available
- Structural context available
- Literature evidence available