G12R (p.Gly12Arg) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
G12R (p.Gly12Arg) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
G12R (p.Gly12Arg) variant details
- p.Gly12Arg
- rs779597599
- gnomAD 14-20343675-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0564
- REVEL 0.04
- CADD 0.11
- PolyPhen-2 0.00
- SIFT 0.85
- Population evidence available
- Structural context available
- Literature evidence available