G11C (p.Gly11Cys) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
G11C (p.Gly11Cys) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
G11C (p.Gly11Cys) variant details
- p.Gly11Cys
- gnomAD 14-20343672-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.129
- REVEL 0.14
- CADD 6.70
- PolyPhen-2 0.57
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available