G10C (p.Gly10Cys) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
G10C (p.Gly10Cys) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
G10C (p.Gly10Cys) variant details
- p.Gly10Cys
- gnomAD 14-20343669-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0778
- REVEL 0.09
- CADD 0.72
- PolyPhen-2 0.47
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available