G10A (p.Gly10Ala) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
G10A (p.Gly10Ala) in PARP2 (Poly [ADP-ribose] polymerase 2) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
G10A (p.Gly10Ala) variant details
- p.Gly10Ala
- rs1461324778
- gnomAD 14-20343666-AC-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.239
- CADD 22.30
- Population evidence available
- Structural context available
- Literature evidence available