C42S (p.Cys42Ser) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
C42S (p.Cys42Ser) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
C42S (p.Cys42Ser) variant details
- p.Cys42Ser
- rs1435242860
- gnomAD 14-20345009-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.05
- CADD 12.90
- PolyPhen-2 0.00
- SIFT 0.92
- Population evidence available
- Structural context available
- Literature evidence available