A3S (p.Ala3Ser) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
A3S (p.Ala3Ser) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
A3S (p.Ala3Ser) variant details
- p.Ala3Ser
- gnomAD 14-20343648-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.03
- CADD 8.10
- PolyPhen-2 0.00
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available