A36D (p.Ala36Asp) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
A36D (p.Ala36Asp) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
A36D (p.Ala36Asp) variant details
- p.Ala36Asp
- rs758917151
- gnomAD 14-20344992-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.05
- CADD 14.80
- PolyPhen-2 0.03
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available