A2G (p.Ala2Gly) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
A2G (p.Ala2Gly) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
A2G (p.Ala2Gly) variant details
- p.Ala2Gly
- gnomAD 14-20343646-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.11
- CADD 27.20
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available