A14S (p.Ala14Ser) variant of PARP2 (Poly [ADP-ribose] polymerase 2)
A14S (p.Ala14Ser) in PARP2 (Poly [ADP-ribose] polymerase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data, published literature, and structural context.
A14S (p.Ala14Ser) variant details
- p.Ala14Ser
- gnomAD 14-20343681-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0396
- REVEL 0.01
- CADD 1.46
- PolyPhen-2 0.04
- SIFT 0.63
- Population evidence available
- Structural context available
- Literature evidence available