T36T (p.Thr36Thr) variant of OPTN (Optineurin)
T36T (p.Thr36Thr) in OPTN (Optineurin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
T36T (p.Thr36Thr) variant details
- p.Thr36Thr
- rs745884191
- gnomAD 10-13109230-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.115
- CADD 4.90
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available
- Literature evidence available