Y19S (p.Tyr19Ser) variant of OPRM1 (Mu-type opioid receptor)
Y19S (p.Tyr19Ser) in OPRM1 (Mu-type opioid receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
Y19S (p.Tyr19Ser) variant details
- p.Tyr19Ser
- gnomAD 6-154039197-TA-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.211
- CADD 18.40
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available