Y19L (p.Tyr19Leu) variant of OPRM1 (Mu-type opioid receptor)
Y19L (p.Tyr19Leu) in OPRM1 (Mu-type opioid receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
Y19L (p.Tyr19Leu) variant details
- p.Tyr19Leu
- gnomAD 6-154039597-CGT-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.23
- CADD 21.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available