Y19H (p.Tyr19His) variant of OPRM1 (Mu-type opioid receptor)
Y19H (p.Tyr19His) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
Y19H (p.Tyr19His) variant details
- p.Tyr19His
- cosmic curated COSV57673
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.13
- CADD 6.46
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available