W31R (p.Trp31Arg) variant of OPRM1 (Mu-type opioid receptor)
W31R (p.Trp31Arg) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
W31R (p.Trp31Arg) variant details
- p.Trp31Arg
- TOPMed rs1423291779
- gnomAD rs1423291779
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.12
- CADD 24.90
- PolyPhen-2 0.07
- SIFT 0.30
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available