V32L (p.Val32Leu) variant of OPRM1 (Mu-type opioid receptor)
V32L (p.Val32Leu) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
V32L (p.Val32Leu) variant details
- p.Val32Leu
- gnomAD rs1160067850
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.06
- CADD 16.30
- PolyPhen-2 0.00
- SIFT 0.92
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available