V32A (p.Val32Ala) variant of OPRM1 (Mu-type opioid receptor)
V32A (p.Val32Ala) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
V32A (p.Val32Ala) variant details
- p.Val32Ala
- gnomAD 6-154039639-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.13
- MetaLR 0.01
- MetaSVM -0.89
- CADD 19.70
- PolyPhen-2 0.01
- SIFT 0.61
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available