T8S (p.Thr8Ser) variant of OPRM1 (Mu-type opioid receptor)
T8S (p.Thr8Ser) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
T8S (p.Thr8Ser) variant details
- p.Thr8Ser
- TOPMed rs1422558678
- Missense
- Variant Prioritization Score for Impact Estimate 0.0457
- REVEL 0.03
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.50
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available