T8K (p.Thr8Lys) variant of OPRM1 (Mu-type opioid receptor)
T8K (p.Thr8Lys) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
T8K (p.Thr8Lys) variant details
- p.Thr8Lys
- gnomAD rs1779597786
- Missense
- Variant Prioritization Score for Impact Estimate 0.0395
- REVEL 0.03
- CADD 0.56
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available