T8H (p.Thr8His) variant of OPRM1 (Mu-type opioid receptor)
T8H (p.Thr8His) in OPRM1 (Mu-type opioid receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
T8H (p.Thr8His) variant details
- p.Thr8His
- rs1554256936
- gnomAD 6-154039560-G-GC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.387
- CADD 22.20
- Most common in the HGDP:MAYA population (allele frequency 0.026)
- Structural context available
- Literature evidence available