T8A (p.Thr8Ala) variant of OPRM1 (Mu-type opioid receptor)
T8A (p.Thr8Ala) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
T8A (p.Thr8Ala) variant details
- p.Thr8Ala
- TOPMed rs1422558678
- Missense
- Variant Prioritization Score for Impact Estimate 0.0483
- REVEL 0.03
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available