S3R (p.Ser3Arg) variant of OPRM1 (Mu-type opioid receptor)
S3R (p.Ser3Arg) in OPRM1 (Mu-type opioid receptor) is a missense change. Clinical records from EBI and UniProt describe it as drug response. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
S3R (p.Ser3Arg) variant details
- p.Ser3Arg
- cosmic curated COSV57678
- ExAC rs747772652
- Drug response
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.27
- CADD 24.80
- PolyPhen-2 0.99
- SIFT 0.00
- EBI: Drug response
- UniProt: Drug response
- Population evidence available
- Structural context available