S35T (p.Ser35Thr) variant of OPRM1 (Mu-type opioid receptor)
S35T (p.Ser35Thr) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
S35T (p.Ser35Thr) variant details
- p.Ser35Thr
- gnomAD 6-154039647-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.17
- MetaLR 0.01
- MetaSVM -1.04
- CADD 21.40
- PolyPhen-2 0.01
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available