S30P (p.Ser30Pro) variant of OPRM1 (Mu-type opioid receptor)
S30P (p.Ser30Pro) in OPRM1 (Mu-type opioid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
S30P (p.Ser30Pro) variant details
- p.Ser30Pro
- gnomAD 6-154039632-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.18
- MetaLR 0.01
- MetaSVM -0.98
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available